Publications


2021

  • Ali MQ, Kohler TP Burchhardt G, Wüst A, Henck N, Bolsmann R, Voß F, Hammerschmidt S. Extracellular Pneumococcal Serine Proteases Affect Nasopharyngeal Colonization. Front. Cell. Infect. Microbiol., 15 February 2021 | https://doi.org/10.3389/fcimb.2020.613467
  • ZaeckLM, Scheibner D, Sehl J, Müller M, Hoffmann D, Beer M, Abdelwhab EM, Mettenleiter TC, Breithaupt A, Finke S. Light Sheet Microscopy-Assisted 3D Analysis of SARS-CoV-2 Infection in the Respiratory Tract of the Ferret Model. Viruses 2021 Mar 23;13(3):529. doi: 10.3390/v13030529. 

2020

  • Abdullah MR, Batuecas MT, Jennert F, Voß F, Westhoff P, Kohler TP, Molina R, Hirschmann S, Lalk M, Hermoso JA, Hammerschmidt S (2020). Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA, Journal of Molecular Biology Volume 433, Issue 2, 22 January 2021, 166723. https://doi.org/10.1016/j.jmb.2020.11.022

  • Gierse LC, Meene A, Schultz D, Schwaiger TKarte C, Schröder C, Wang H, Wünsche C, Methling K, Kreikemeyer B, Fuchs S, Bernhardt J, Becher DLalk MKoInfekt Study Group, Urich T, Riedel K (2020). A Multi-Omics Protocol for Swine Feces to Elucidate Longitudinal Dynamics in Microbiome Structure and Function. Microorganisms 2020, 8, 1887; doi:10.3390/microorganisms8121887

  • Potratz M, Zaeck LM, Weigel C, Klein A, Freuling CM, Müller T, Finke S (2020). Neuroglia infection by rabies virus after anterograde virus spread in peripheral neurons. Acta Neuropathol Commun 2020 Nov 23;8(1):199.  doi: 10.1186/s40478-020-01074-6. PubMed

  • Siemens N, Snäll J, Svensson M, Norrby-Teglund A (2020). Pathogenic Mechanisms of Streptococcal Necrotizing Soft Tissue Infections. Adv Exp Med Biol. 2020;1294:127-150. doi: 10.1007/978-3-030-57616-5_9. PubMed

  • Volzke V, Schultz D, Kordt M, Müller M, Bergmann W, Methling K, Kreikemeyer B, Müller-Hilke B, KoInfekt Study Group (2020). Inflammatory Joint Disease Is a Risk Factor for Streptococcal Sepsis and Septic Arthritis in Mice. doi: 10.3389/fimmu.2020.579475 Frontiers

  • Matthiesen S, Zaeck L, Franzke K, Jahnke R, Fricke C, Mauermeir M, Finke S, Lührmann A, KnittlerMR (2020). Coxiella burnetii-infected NK cells release infectious bacteria by degranulation. Infect Immun IAI.00172-20. doi: 10.1128/IAI.00172-20. Online ahead of print. PubMed

  • Schweinoch D, Bachmann P, Clausznitzer D, Binder M, Kaderali  L (2020). Mechanistic modeling explains the dsRNA lengthdependent activation of the RIG-I mediated immune response. J Theor Biol 2020 Sep 7;500:110336.  doi: 10.1016/j.jtbi.2020.110336. PubMed

  • Cuypers F, Klabunde B, Gesell Salazar M, Surabhi S, Skorka SB, Burchhardt G, Michalik S, Thiele T, Rohde M, Völker U, Hammerschmidt S, Siemens N (2020). Adenosine Triphosphate Neutralizes Pneumolysin-induced Neutrophil Activation. J Infect Dis 2020 May 23;jiaa277. doi: 10.1093/infdis/jiaa277. PubMed

  • Oehmcke-Hecht S, Mandl V, Naatz LT, Dühring L, Köhler J, Kreikemeyer B, Maletzki C. Streptococcus gallolyticus abrogates anti-carcinogenic properties of tannic acid on low-passage colorectal carcinomas. Sci Rep. 2020 Mar 13;10(1):4714. doi: 10.1038/s41598-020-61458-5.

  • KöhlerJ, Ehler J, Kreikemeyer B, Bajorath R, Schürholz T, Oehmcke-Hecht S. The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma. Sci Rep 2020 Apr 28;10(1):7142. doi: 10.1038/s41598-020-64155-5. PubMed

  • Potratz M, Zaeck L, Christen M, Te Kamp V, Klein A, Nolden T, Freuling CM, Müller T, Finke S. Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism. Cells 11;9(2). pii: E412. doi: 10.3390/cells9020412. MDPI

  • SchultzD, Surabhi S, Stelling N, Rothe M, KoInfekt Study Group, Methling K, HammerschmidtS, Siemens N, Lalk M. 16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens. Metabolites 2020, 10(3), 113; doi.org/10.3390/metabo10030113. PubMed

  • Leonard A, Möhlis K, Schlüter R, Taylor E, Lalk M, Methling K. Exploring metabolic adaptation of Streptococcus pneumoniae to antibiotics. The Journal of Antibiotics volume 73, pages441–454(2020). PubMed
  • Voß F, van Beek LF, Schwudke D, Ederveen THA, van Opzeeland FJ, Thalheim D, Werner S, de Jonge MI, Hammerschmidt S. Lipidation of Pneumococcal Antigens Leads to Improved Immunogenicity and Protection. Vaccines (Basel) 2020 Jun 17;8(2):E310. doi: 10.3390/vaccines8020310. PubMed

2019

  • Söllinger A, Urich T*. Methylotrophic methanogens everywhere - physiology and ecology of novel players in global methane cycling. Biochemical Society Transactions 2019 47 (6), 1895-1907. PubMed​​​​​​​

  • Schwaiger T, Sehl J, Karte C, Schäfer A, Hühr J, Mettenleiter TC, Schröder C, Köllner B, Ulrich R, Blohm U. Experimental H1N1pdm09 infection in pigs mimics human seasonal influenza infections. PLOS ONE 2019, 14 (9), e0222943. PubMed

  • Barkowsky G, Lemster A-L, Pappesch R, Jacob A, Krüger S, Schröder A, Kreikemeyer B, Patenge N. Influence of different Cell-Penetrating Peptides on the antimicrobial efficiency of antisense Peptide Nucleic Acids in Streptococcus pyogenes. Mol.Ther.Nucleic Acids. 2019 Dec 6; 18: 444–454. doi: 10.1016/j.omtn.2019.09.010. PubMed

  • Schultz D, Methling K, KoInfekt Study Group, Rothe M, Lalk M. Eicosanoid Profile of Influenza A Virus Infected Pigs. Metabolites. 2019 Jul 3;9(7). pii: E130. doi: 10.3390/metabo9070130. PubMed

  • Schäfer A, Hühr J, Schwaiger T, Dorhoi A, Mettenleiter TC, Blome S, Schröder C, Blohm U. Porcine Invariant Natural Killer T Cells: Functional Profiling and Dynamics in Steady State and Viral Infections. Front Immunol. 2019 Jun 18;10:1380. doi: 10.3389/fimmu.2019.01380. eCollection 2019. PubMed

  • Shumba P, Mairpady Shambat S, Siemens N. The role of streptococcal and staphylococcal exotoxins and proteases in human necrotizing soft tissue infections.  Toxins (Basel). 2019 Jun 11;11(6). pii: E332. doi: 10.3390/toxins11060332. PubMed

  • Zaeck L, Potratz M, Freuling CM, Müller T, Finke S.  High-Resolution 3D Imaging of Rabies Virus Infection in Solvent-Cleared BrainTissue. Journal of Visualized Experiments (146), e59402, doi:10.3791/59402 (2019). JoVe video

2018

  • Darisipudi MN, Nordengrün M, Bröker BM, Pèton V. Messing with the Sentinels - The Interaction of Staphylococcus aureus with Dendritic Cells. Microorganisms  6 (3): 87 (2018). PubMed
  • Traxler S, Bischoff A-C, Saß R, Trefz P, Gierschner P, Brock B, Schwaiger T, Karte C, Blohm U,  Schröder C, Miekisch W, Schubert JK. VOC breath profile in spontaneously breathing awake swine during Influenza A infection. Scientific Reports 8 (1): 14857 (2018). PubMed
  • Nordengrün M, Michalik S, Völker U, Bröker BM, Gómez-Gascón L. The quest for bacterial allergens. International Journal of Medical Microbiology 308 (6): 738-750 (2018). PubMed
  • Traxler S, Bischoff A-C, Trefz P, Schubert JK, Miekisch W. Versatile set-up for non-invasive in vitro analysis of headspace VOCs. J Breath Res 2018;12(4):041001. doi: 10.1088/1752-7163/aaccad. PubMed
  • Jarick M, Bertsche U, Stahl M, Schultz D, Methling KLalk M, Stigloher C, Steger M, Schlosser A, Ohlsen K. The serine/threonine kinase Stk and the phosphatase Stp regulate cell wall synthesis in Staphylococcus aureus. Sci Rep 2018; 8(1):13693. doi: 10.1038/s41598-018-32109-7. PubMed
  • Hoyer J, Bartel J, Gómez-Mejia A, Rohde M, Hirschfeld C, Heß N, Sura T, Maaß S, Hammerschmidt SBecher D. Proteomic response of Streptococcus pneumoniae to iron limitation. Int J Med Microbiol 2018; pii: S1438-4221(17)30471-X. doi: 10.1016/j.ijmm.2018.02.001. [Epub ahead of print] PubMed
  • Oehmcke-Hecht S, Köhler J. Interaction of the human contact system with pathogens - an update. Front Immunol 2018; 9:312. Frontiers
  • Khani A, Popp N, Kreikemeyer BPatenge N. A Glycine Riboswitch in Streptococcus pyogenes controls Expression of a Sodium: Alanine Symporter Family Protein Gene. Front Microbiol 2018; 9:200. Frontiers 

     

2017

  • Siemens NOehmcke-Hecht SMettenleiter TCKreikemeyer B, Valentin-Weigand P, Hammerschmidt S. Port d'Entrée for Respiratory Infections - Does the Influenza A Virus Pave the Way for Bacteria? Front Microbiol 2017; 8:2602. PubMed