EFRE-Funding

In various projects of the department, it will be clarified how far monocausal infections with viral and bacterial pathogens, e.g. pneumococci, staphylococci and streptococci or co-infections (bakto-viral infections) influence the composition of the immune compartments in circulation and at the primary site of infection.

Furthermore, a research group is working with the biotechnology of the central cellular metabolite coenzyme A (CoA) in yeast. It will be investigated whether "metabolic engineering" increases the amount of CoA, which is limiting for many basic metabolic processes and therefore limits e.g. the currently possible yield of biofuels, and thus ultimately provides a production organism optimized for interested industrial partners.

In addition to infection biology and interactive studies, application-oriented work with economic potential,e.g. such as efficacy studies of vaccine candidates in cellular systems, interaction studies of diagnostically usable bacterial proteins, functional studies of genetically modified multienzyme complexes, are also tested and evaluated. With funding from the European Union (ERDF - European Regional Development Fund), it is now possible for us to perform such studies extensively. The three devices, high-speed cell sorting system FACSAria III, LUNARIS Reader and Monolith NT.115, allow us to specifically investigate complex interactions and immune responses on a single-cell basis.

Poster EFRE FACSAria III + LUNARIS
Poster EFRE Monolith NT.115