Dr. Elke Hammer
Gruppenleiterin
Interfakultäres Institut für Genetik und Funktionelle Genomforschung
Felix-Hausdorff-Straße 8
D-17475 Greifswald
Büro: Raum 2.61
Telefon +49 3834 420 5811
Telefax +49 3834 420 5890
Forschungsinteressen
- Personalisierte Medizin
- Funktionelle Genomforschung für Biomarkerscreening
- Kardiovaskuläre Medizin
- Zell-Zell-Kommunikation durch sekretierte Proteine
- Analyse von Protein-Protein-Interaktionen
Publikationen
2024
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Dörmann N, Hammer E, Struckmann K, Rüdebusch J, Bartels K, Wenzel K, Schulz J, Gross S, Schwanz S, Martin E, Fielitz B, Pablo Tortola C, Hahn A, Benkner A, Völker U, Felix SB, Fielitz J (2023) Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice. Front Cardiovasc Med. 10:1323760. ArtikelPubmedRelated |
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Kliewe F, Siegerist F, Hammer E, Al-Hasani J, Amling TRJ, Hollemann JZE, Schindler M, Drenic V, Simm S, Amann K, Daniel C, Lindenmeyer M, Hecker M, Völker U, Endlich N (2024) Zyxin is important for the stability and function of podocytes, especially during mechanical stretch. Commun Biol. 7:446. ArtikelPubmedRelated |
2023
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Bernhardt A, Krause A, Reichardt C, Steffen H, Isermann B, Völker U, Hammer E, Geffers R, Philipsen L, Dhjamandi K, Ahmad S, Brandt S, Lindquist JA, Mertens PR (2023) Excessive sodium chloride ingestion promotes inflammation and kidney fibrosis in aging mice. Am J Physiol Cell Physiol. 325:C456-C470. ArtikelPubmedRelated |
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Ebstein F, Küry S, Most V, Rosenfelt C, Scott-Boyer M, van Woerden GM, Besnard T, Papendorf JJ, Studencka-Turski M, Wang T, Hsieh T, Golnik R, Baldridge D, Forster C, de Konink C, Teurlings SMW, Vignard V, van Jaarsveld RH, Ades L, Cogné B, Mignot C, Deb W, Jongmans MCJ, Cole FS, van den Boogaard MH, Wambach JA, Wegner DJ, Yang S, Hannig V, Brault JA, Zadeh N, Bennetts B, Keren B, Gélineau A, Powis Z, Towne M, Bachman K, Seeley A, Beck AE, Morrison J, Westman R, Averill K, Brunet T, Haasters J, Carter MT, Osmond M, Wheeler PG, Forzano F, Mohammed S, Trakadis Y, Accogli A, Harrison R, Guo Y, Hakonarson H, Rondeau S, Baujat G, Barcia G, Feichtinger RG, Mayr JA, Preisel M, Laumonnier F, Kallinich T, Knaus A, Isidor B, Krawitz P, Völker U, Hammer E, Droit A, Eichler EE, Elgersma Y, Hildebrand PW, Bolduc F, Krüger E, Bézieau S (2023) PSMC3 proteasome subunit variants are associated with neurodevelopmental delay and type I interferon production. Sci Transl Med. 15:eabo3189. ArtikelPubmedRelated |
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Holst T, Petersen J, Ameling S, Müller L, Christ T, Gedeon N, Eschenhagen T, Reichenspurner H, Hammer E, Girdauskas E (2023) Proteomic Analysis in Valvular Cardiomyopathy: Aortic Regurgitation vs. Aortic Stenosis. Cells. 12:878. ArtikelPubmedRelated |
| Reder A, Hentschker C, Steil L, Gesell Salazar M, Hammer E, Dhople VM, Sura T, Lissner U, Wolfgramm H, Dittmar D, Harms M, Surmann K, Völker U, Michalik S (2023) MassSpecPreppy-An end-to-end solution for automated protein concentration determination and flexible sample digestion for proteomics applications. Proteomics. ArtikelPubmedRelated |
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Venz S, von Bohlen Und Halbach V, Hentschker C, Junker H, Kuss AW, Sura T, Krüger E, Völker U, von Bohlen Und Halbach O, Jensen LR, Hammer E (2023) Global Protein Profiling in Processed Immunohistochemistry Tissue Sections. Int J Mol Sci. 24:11308. ArtikelPubmedRelated |
2022
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Assum I, Krause J, Scheinhardt MO, Müller C, Hammer E, Börschel CS, Völker U, Conradi L, Geelhoed B, Zeller T, Schnabel RB, Heinig M (2022) Tissue-specific multi-omics analysis of atrial fibrillation. Nat Commun. 13:441. ArtikelPubmedRelated |
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Benkner A, Rüdebusch J, Nath N, Hammer E, Grube K, Gross S, Dhople VM, Eckstein G, Meitinger T, Kaderali L, Völker U, Fielitz J, Felix SB (2022) Riociguat attenuates left ventricular proteome and microRNA profile changes after experimental aortic stenosis in mice. Br J Pharmacol. 2013:53-56. ArtikelPubmedRelated |
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Çetin G, Studencka-Turski M, Venz S, Schormann E, Junker H, Hammer E, Völker U, Ebstein F, Krüger E (2022) Immunoproteasomes control activation of innate immune signaling and microglial function. Front Immunol. 13:982786. ArtikelPubmedRelated |
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Forkel H, Grabarczyk P, Depke M, Troschke-Meurer S, Simm S, Hammer E, Michalik S, Hentschker C, Corleis B, Loyal L, Zumpe M, Siebert N, Dorhoi A, Thiel A, Lode H, Völker U, Schmidt CA (2022) BCL11B depletion induces the development of highly cytotoxic innate T cells out of IL-15 stimulated peripheral blood $\alpha$β CD8+ T cells. Oncoimmunology. 11:2148850. ArtikelPubmedRelated |
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Gencheva S, Dersch S, Surmann K, Wernet M, Antelo L, Hammer E, Graumann PL, Hellmann N, Unden G (2022) Tight Complex Formation of the Fumarate Sensing DcuS-DcuR Two-Component System at the Membrane and Target Promoter Search by Free DcuR Diffusion. mSphere. ArtikelPubmedRelated |
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Lorenz M, Witt E, Völker U, Stangl K, Stangl V, Hammer E (2022) Serum starvation induces sexual dimorphisms in secreted proteins of human umbilical vein endothelial cells (HUVECs) from twin pairs. Proteomics. ArtikelPubmedRelated |
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Sunny DE, Krüger EL, Hammer E, Völker U, Heckmann M (2022) Fetal Zone Steroids Show Discrete Effects on Hyperoxia-Induced Attenuation of Migration in Cultured Oligodendrocyte Progenitor Cells. Oxid Med Cell Longev. 2022:2606880. ArtikelPubmedRelated |
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von Bohlen Und Halbach V, Venz S, Nwakor S, Hentschker C, Hammer E, Junker H, Kuss AW, von Bohlen Und Halbach O, Jensen LR (2022) Deficiency in FTSJ1 Affects Neuronal Plasticity in the Hippocampal Formation of Mice. Biology. 11:1011. ArtikelPubmedRelated |
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Zech ATL, Prondzynski M, Singh SR, Pietsch N, Orthey E, Alizoti E, Busch J, Madsen A, Behrens CS, Meyer-Jens M, Mearini G, Lemoine MD, Krämer E, Mosqueira D, Virdi S, Indenbirken D, Depke M, Gesell Salazar M, Völker U, Braren I, Pu WT, Eschenhagen T, Hammer E, Schlossarek S, Carrier L (2022) ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes. Cells. 11:2745. ArtikelPubmedRelated |
2021
| Ameling S, Bischof J, Dörr M, Könemann S, Empen K, Weitmann K, Klingel K, Beug D, Dhople VM, Völker U, Hammer E, Felix SB (2021) Analysis of DCM associated protein alterations of human right and left ventricles. J Proteomics. 231:104018. ArtikelPubmedRelated |
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Bräuninger H, Thottakara T, Schön J, Voss S, Dhople V, Warnke S, Scherschel K, Schrage B, Kirchhof P, Blankenberg S, Völker U, Westermann D, Hammer E, Lindner D (2021) Cytokine-Mediated Alterations of Human Cardiac Fibroblast's Secretome Int J Mol Sci. 22:12262. ArtikelPubmedRelated |
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Buchholz I, McDonnell T, Nestler P, Tharad S, Kulke M, Radziszewska A, Ripoll VM, Schmidt F, Hammer E, Toca-Herrera JL, Rahman A, Delcea M (2021) Specific domain V reduction of beta-2-glycoprotein I induces protein flexibility and alters pathogenic antibody binding. Sci Rep. 11:4542. ArtikelPubmedRelated |
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de Freitas Chama LL, Ebstein F, Wiesrecker B, Wagh PR, Hammer E, Weiss FU, Junker H, Studencka-Turski M, Lerch MM, Krüger E, Sendler M (2021) Immunoproteasome impairment via β5i/LMP7-deletion leads to sustained pancreatic injury from experimental pancreatitis. J Cell Mol Med. ArtikelPubmedRelated |
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Elhag S, Stremmel C, Zehrer A, Plocke J, Hennel R, Keuper M, Knabe C, Winterhalter J, Gölling V, Tomas L, Weinberger T, Fischer M, Liu L, Wagner F, Lorenz M, Stark K, Häcker H, Schmidt-Supprian M, Völker U, Jastroch M, Lauber K, Straub T, Walzog B, Hammer E, Schulz C (2021) Differences in Cell-Intrinsic Inflammatory Programs of Yolk Sac and Bone Marrow Macrophages. Cells. 10:3564. ArtikelPubmedRelated |
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Sunny DE, Hammer E, Ittermann T, Krüger EL, Hübner S, Hartmann MF, Wudy SA, Völker U, Heckmann M (2021) Fetal Zone Steroids and Estrogen Show Sex Specific Effects on Oligodendrocyte Precursor Cells in Response to Oxidative Damage. Int J Mol Sci. 22:6586. ArtikelPubmedRelated |
2020
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Howland V, Klaedtke M, Ruhnau J, Dhople VM, Grabe HJ, Völker U, Heckmann M, Hammer E (2020) Impact of Storage Conditions on the Breast Milk Peptidome. Nutrients. 12:2733. ArtikelPubmedRelated |
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Ilieș M, Uifălean A, Pașca S, Dhople VM, Lalk M, Iuga CA, Hammer E (2020) From Proteomics to Personalized Medicine: The Importance of Isoflavone Dose and Estrogen Receptor Status in Breast Cancer Cells. J Pers Med. 10:292. ArtikelPubmedRelated |
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Mikolasch A, Hammer E, Witt S, Lindequist U (2020) Laccase-catalyzed derivatization of 6-aminopenicillanic, 7-aminocephalosporanic and 7-aminodesacetoxycephalosporanic acid. AMB Express. 10:177. ArtikelPubmedRelated |
| Rath H, Reder A, Hoffmann T, Hammer E, Seubert A, Bremer E, Völker U, Mäder U (2020) Management of Osmoprotectant Uptake Hierarchy in Bacillus subtilis via a SigB-Dependent Antisense RNA. Front Microbiol. 11:622. ArtikelPubmedRelated |
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Sunny DE, Hammer E, Strempel S, Joseph C, Manchanda H, Ittermann T, Hübner S, Weiss FU, Völker U, Heckmann M (2020) Nup133 and ER$\alpha$ mediate the differential effects of hyperoxia-induced damage in male and female OPCs. Mol Cell Pediatr. 7:10. ArtikelPubmedRelated |
| Surmann K, Stopp M, Wörner S, Dhople VM, Völker U, Unden G, Hammer E (2020) Fumarate dependent protein composition under aerobic and anaerobic growth conditions in Escherichia coli. J Proteomics. 212:103583. ArtikelPubmedRelated |
2019
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Feig MA, Pop C, Bhardwaj G, Sappa PK, Dörr M, Ameling S, Weitmann K, Nauck M, Lehnert K, Beug D, Kühl U, Schultheiss H, Völker U, Felix SB, Hammer E (2019) Global plasma protein profiling reveals DCM characteristic protein signatures. J Proteomics. 209:103508. ArtikelPubmedRelated |
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Krauel K, Preuße P, Warkentin TE, Trabhardt C, Brandt S, Jensch I, Mandelkow M, Hammer E, Hammerschmidt S, Greinacher A (2019) Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT. Blood. 133:978-989. ArtikelPubmedRelated |
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Lorenz M, Blaschke B, Benn A, Hammer E, Witt E, Kirwan J, Fritsche-Guenther R, Gloaguen Y, Bartsch C, Vietzke A, Kramer F, Kappert K, Brunner P, Nguyen HG, Dreger H, Stangl K, Knaus P, Stangl V (2019) Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs. Atherosclerosis. 291:99-106. ArtikelPubmedRelated |
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Quintana IM, Gibhardt J, Turdiev A, Hammer E, Commichau FM, Lee VT, Magni C, Stülke J (2019) The KupA and KupB Proteins of Lactococcus lactis IL1403 Are Novel c-di-AMP Receptor Proteins Responsible for Potassium Uptake. J Bacteriol. 201:1-13. ArtikelPubmedRelated |
| Samal R, Sappa PK, Gesell Salazar M, Wenzel K, Reinke Y, Völker U, Felix SB, Hammer E, Könemann S (2019) Global secretome analysis of resident cardiac progenitor cells from wild-type and transgenic heart failure mice: Why ambience matters. J Cell Physiol. 234:10111-10122. ArtikelPubmedRelated |
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Scholz B, Schulte JS, Hamer S, Himmler K, Pluteanu F, Seidl MD, Stein J, Wardelmann E, Hammer E, Völker U, Müller FU (2019) HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice. Circ Arrhythm Electrophysiol. 12:e007071. ArtikelPubmedRelated |
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Winter J, Hammer E, Heger J, Schultheiss H, Rauch U, Landmesser U, Dörner A (2019) Adenine Nucleotide Translocase 1 Expression is Coupled to the HSP27-Mediated TLR4 Signaling in Cardiomyocytes. Cells. 8:1588. ArtikelPubmedRelated |
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Witt E, Lorenz M, Völker U, Stangl K, Hammer E, Stangl V (2019) Sex-specific differences in the intracellular proteome of human endothelial cells from dizygotic twins. J Proteomics. 201:48-56. ArtikelPubmedRelated |
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Witt E, Hammer E, Dörr M, Weitmann K, Beug D, Lehnert K, Nauck M, Völker U, Felix SB, Ameling S (2019) Correlation of gene expression and clinical parameters identifies a set of genes reflecting LV systolic dysfunction and morphological alterations. Physiol Genomics. 51:356-367. ArtikelPubmedRelated |
2018
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Grabarczyk P, Winkler P, Delin M, Sappa PK, Bekeschus S, Hildebrandt P, Przybylski GK, Völker U, Hammer E, Schmidt CA (2017) The N-Terminal CCHC Zinc Finger Motif Mediates Homodimerization of Transcription Factor BCL11B Mol Cell Biol. 38:e00368-17. ArtikelPubmedRelated |
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Ilies M, Sappa PK, Iuga CA, Loghin F, Gesell Salazar M, Weiss FU, Beyer G, Lerch MM, Völker U, Mayerle J, Hammer E (2018) Plasma protein profiling of patients with intraductal papillary mucinous neoplasm of the pancreas as potential precursor lesions of pancreatic cancer Clin Chim Acta. 477:127-134. ArtikelPubmedRelated |
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Kirchhefer U, Hammer E, Heinick A, Herpertz T, Isensee G, Müller FU, Neumann J, Schulte K, Seidl MD, Boknik P, Schulte JS (2018) Chronic β-adrenergic stimulation reverses depressed Ca handling in mice overexpressing inhibitor-2 of protein phosphatase 1 J Mol Cell Cardiol. 125:195-204. ArtikelPubmedRelated |
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Kornej J, Büttner P, Hammer E, Engelmann B, Dinov B, Sommer P, Husser D, Hindricks G, Völker U, Bollmann A (2018) Circulating proteomic patterns in AF related left atrial remodeling indicate involvement of coagulation and complement cascade PLoS One. 13:e0198461. ArtikelPubmedRelated |
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Wörner S, Surmann K, Ebert-Jung A, Völker U, Hammer E, Undena G (2018) Cellular concentrations of the transporters DctA and DcuB and the sensor DcuS of Escherichia coli and the contributions of free and complexed DcuS to transcriptional regulation by DcuR J Bacteriol. 200:e00612-17. ArtikelPubmedRelated |
2017
| Bhardwaj G, Dörr M, Sappa PK, Ameling S, Dhople V, Steil L, Klingel K, Empen K, Beug D, Völker U, Felix SB, Hammer E (2017) Endomyocardial proteomic signature corresponding to the response of patients with dilated cardiomyopathy to immunoadsorption therapy. J Proteomics. 150:121-129. ArtikelPubmedRelated |
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Blötz C, Treffon K, Kaever V, Schwede F, Hammer E, Stülke J (2017) Identification of the Components Involved in Cyclic Di-AMP Signaling in Mycoplasma pneumoniae. Front Microbiol. 8:1328. ArtikelPubmedRelated |
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Ćudić E, Surmann K, Panasia G, Hammer E, Hunke S (2017) The role of the two-component systems Cpx and Arc in protein alterations upon gentamicin treatment in . BMC Microbiol. 17:197. ArtikelPubmedRelated |
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Ilies M, Iuga CA, Loghin F, Dhople VM, Thiele T, Völker U, Hammer E (2017) Data on the impact of the blood sample collection methods on blood protein profiling studies. Data Brief. 14:313-319. ArtikelPubmedRelated |
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Ilies M, Iuga CA, Loghin F, Dhople VM, Hammer E (2017) Plasma protein absolute quantification by nano-LC Q-TOF UDMSE for clinical biomarker verification. Clujul Med. 90:425-430. ArtikelPubmedRelated |
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Ilies M, Iuga CA, Loghin F, Dhople VM, Thiele T, Völker U, Hammer E (2017) Impact of blood sample collection methods on blood protein profiling studies. Clin Chim Acta. 471:128-134. ArtikelPubmedRelated |
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Kindt F, Hammer E, Kemnitz S, Blumenthal A, Klemm P, Schlüter R, Quaggin SE, van den Brandt J, Fuellen G, Völker U, Endlich K, Endlich N (2017) A novel assay to assess the effect of pharmaceutical compounds on the differentiation of podocytes. Br J Pharmacol. 174:163-176. ArtikelPubmedRelated |
| Michalik S, Depke M, Murr A, Gesell Salazar M, Kusebauch U, Sun Z, Meyer TC, Surmann K, Pförtner H, Hildebrandt P, Weiss S, Palma Medina LM, Gutjahr M, Hammer E, Becher D, Pribyl T, Hammerschmidt S, Deutsch EW, Bader SL, Hecker M, Moritz RL, Mäder U, Völker U, Schmidt F (2017) A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions. Sci Rep. 7:9718. ArtikelPubmedRelated |
| Murr A, Pink C, Hammer E, Michalik S, Dhople VM, Holtfreter B, Völker U, Kocher T, Gesell Salazar M (2017) Cross-Sectional Association of Salivary Proteins with Age, Sex, Body Mass Index, Smoking, and Education. J Proteome Res. 16:2273-2281. ArtikelPubmedRelated |
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Pietzner M, Engelmann B, Kacprowski T, Golchert J, Dirk A, Hammer E, Iwen KA, Nauck M, Wallaschofski H, Führer D, Münte TF, Friedrich N, Völker U, Homuth G, Brabant G (2017) Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model. BMC Med. 15:6. ArtikelPubmedRelated |
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Rüdebusch J, Benkner A, Poesch A, Dörr M, Völker U, Grube K, Hammer E, Felix SB (2017) Dynamic adaptation of myocardial proteome during heart failure development. PLoS One. 12:e0185915. ArtikelPubmedRelated |
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Schaletzki Y, Kromrey M, Bröderdorf S, Hammer E, Grube M, Hagen P, Sucic S, Freissmuth M, Völker U, Greinacher A, Rauch BH, Kroemer HK, Jedlitschky G (2017) Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells. Thromb Haemost. 117:105-115. ArtikelPubmedRelated |
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Seidl MD, Stein J, Hamer S, Pluteanu F, Scholz B, Wardelmann E, Huge A, Witten A, Stoll M, Hammer E, Völker U, Müller FU (2017) Characterization of the Genetic Program Linked to the Development of Atrial Fibrillation in CREM-Ib$\Delta$C-X Mice. Circ Arrhythm Electrophysiol. 10. ArtikelPubmedRelated |
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Wenzel K, Samal R, Hammer E, Dhople VM, Gross S, Völker U, Felix SB, Könemann S (2017) Pathophysiological aldosterone levels modify the secretory activity of cardiac progenitor cells. Mol Cell Endocrinol. 439:16-25. ArtikelPubmedRelated |
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Zühlke M, Schlüter R, Mikolasch A, Zühlke D, Giersberg M, Schindler H, Henning A, Frenzel H, Hammer E, Lalk M, Bornscheuer UT, Riedel K, Kunze G, Schauer F (2017) Biotransformation and reduction of estrogenicity of bisphenol A by the biphenyl-degrading Cupriavidus basilensis. Appl Microbiol Biotechnol. 101:3743-3758. ArtikelPubmedRelated |
2016
| Ameling S, Bhardwaj G, Hammer E, Beug D, Steil L, Reinke Y, Weitmann K, Grube M, Trimpert C, Klingel K, Kandolf R, Hoffmann W, Nauck M, Dörr M, Empen K, Felix SB, Völker U (2016) Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution. Basic Res Cardiol. 111:53. ArtikelPubmedRelated |
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Mikolasch A, Hildebrandt O, Schlüter R, Hammer E, Witt S, Lindequist U (2016) Targeted synthesis of novel $\beta$-lactam antibiotics by laccase-catalyzed reaction of aromatic substrates selected by pre-testing for their antimicrobial and cytotoxic activity. Appl Microbiol Biotechnol. 100:4885-99. ArtikelPubmedRelated |
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Saafan H, Foerster S, Parra-Guillen ZP, Hammer E, Michaelis M, Cinatl J, Völker U, Fröhlich H, Kloft C, Ritter CA (2016) Utilising the EGFR interactome to identify mechanisms of drug resistance in non-small cell lung cancer - Proof of concept towards a systems pharmacology approach. Eur J Pharm Sci. 94:20-32. ArtikelPubmedRelated |
| Surmann K, Ćudić E, Hammer E, Hunke S (2016) Molecular and proteome analyses highlight the importance of the Cpx envelope stress system for acid stress and cell wall stability in . Microbiologyopen. 5:582-96. ArtikelPubmedRelated |
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Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, CHARGE Longevity Working Group , Cappola A, Ceda GP, Chanock S, Chen M, Chen TC, Chen YI, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JAMJL, Jansson J, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJF, Body Composition Genetics Consortium , Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh H, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC (2016) Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 15:811-24. ArtikelPubmedRelated |
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Thiele T, Braune J, Dhople V, Hammer E, Scharf C, Greinacher A, Völker U, Steil L (2016) Proteomic profile of platelets during reconstitution of platelet counts after apheresis. Proteomics Clin Appl. 10:831-8. ArtikelPubmedRelated |
2015
| Ameling S, Kacprowski T, Chilukoti RK, Malsch C, Liebscher V, Suhre K, Pietzner M, Friedrich N, Homuth G, Hammer E, Völker U (2015) Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study. BMC Med Genomics. 8:61. ArtikelPubmedRelated |
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Dormeyer M, Egelkamp R, Thiele MJ, Hammer E, Gunka K, Stannek L, Völker U, Commichau FM (2015) A novel engineering tool in the toolbox: inducer-free activation of gene expression by selection-driven promoter decryptification. Microbiology. 161:354-61. ArtikelPubmedRelated |
| Engelmann B, Bischof J, Dirk A, Friedrich N, Hammer E, Thiele T, Führer D, Homuth G, Brabant G, Völker U (2015) Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study. Eur Thyroid J. 4:119-24. ArtikelPubmedRelated |
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Gundlach J, Dickmanns A, Schröder-Tittmann K, Neumann P, Kaesler J, Kampf J, Herzberg C, Hammer E, Schwede F, Kaever V, Tittmann K, Stülke J, Ficner R (2015) Identification, characterization, and structure analysis of the cyclic di-AMP-binding PII-like signal transduction protein DarA. J Biol Chem. 290:3069-80. ArtikelPubmedRelated |
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Könemann S, Wenzel K, Ameling S, Grube K, Hammer E, Könemann R, Samal R, Völker U, Felix SB (2015) The Other Side of the RAAS: Aldosterone Improves Migration of Cardiac Progenitor Cells. J Cell Physiol. 230:2829-36. ArtikelPubmedRelated |
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Muschter S, Berthold T, Bhardwaj G, Hammer E, Dhople VM, Wesche J, Reil A, Bux J, Bakchoul T, Steil L, Greinacher A, Völker U (2015) Mass spectrometric phosphoproteome analysis of small-sized samples of human neutrophils. Clin Chim Acta. 451:199-207. ArtikelPubmedRelated |
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Phong TQ, Ha DTT, Volker U, Hammer E (2015) Using a Label Free Quantitative Proteomics Approach to Identify Changes in Protein Abundance in Multidrug-Resistant Mycobacterium tuberculosis. Indian J Microbiol. 55:219-30. ArtikelPubmedRelated |
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Pop C, Ameling S, Empen K, Rüdebusch J, Dhople VM, Felix SB, Loghin F, Völker U, Hammer E (2015) Proteome analysis of heart biopsies using a TRIzol-based protein extraction. Clin Chim Acta. 438:246-7. ArtikelPubmedRelated |
| Samal R, Ameling S, Dhople V, Sappa PK, Wenzel K, Völker U, Felix SB, Hammer E, Könemann S (2015) Brain derived neurotrophic factor contributes to the cardiogenic potential of adult resident progenitor cells in failing murine heart. PLoS One. 10:e0120360. ArtikelPubmedRelated |
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Schwebe M, Ameling S, Hammer E, Monzel JV, Bonitz K, Budde S, Schult K, Oswald S, Scheuch E, Grube M, Poesch A, Budde T, Ewert R, Schroeder HWS, Kroemer HK, Bien-Möller S (2015) Protective effects of endothelin receptor A and B inhibitors against doxorubicin-induced cardiomyopathy. Biochem Pharmacol. 94:109-29. ArtikelPubmedRelated |
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Stannek L, Thiele MJ, Ischebeck T, Gunka K, Hammer E, Völker U, Commichau FM (2015) Evidence for synergistic control of glutamate biosynthesis by glutamate dehydrogenases and glutamate in . Environ Microbiol. 17:3379-90. ArtikelPubmedRelated |
2014
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Grabe HJ, Assel H, Bahls T, Dörr M, Endlich K, Endlich N, Erdmann P, Ewert R, Felix SB, Fiene B, Fischer T, Flessa S, Friedrich N, Gadebusch-Bondio M, Salazar MG, Hammer E, Haring R, Havemann C, Hecker M, Hoffmann W, Holtfreter B, Kacprowski T, Klein K, Kocher T, Kock H, Krafczyk J, Kuhn J, Langanke M, Lendeckel U, Lerch MM, Lieb W, Lorbeer R, Mayerle J, Meissner K, zu Schwabedissen HM, Nauck M, Ott K, Rathmann W, Rettig R, Richardt C, Saljé K, Schminke U, Schulz A, Schwab M, Siegmund W, Stracke S, Suhre K, Ueffing M, Ungerer S, Völker U, Völzke H, Wallaschofski H, Werner V, Zygmunt MT, Kroemer HK (2014) Cohort profile: Greifswald approach to individualized medicine (GANI{\_}MED). J Transl Med. 12:144. ArtikelPubmedRelated |
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Gröbetal T, Hammer E, Bien-Möller S, Geisler A, Pinkert S, Röger C, Poller W, Kurreck J, Völker U, Vetter R, Fechner H (2014) A novel artificial microRNA expressing AAV vector for phospholamban silencing in cardiomyocytes improves Ca2+ uptake into the sarcoplasmic reticulum. PLoS One. 9:e92188. ArtikelPubmedRelated |
| Hammer E, Ernst FD, Thiele A, Karanam NK, Kujath C, Evert M, Völker U, Barthlen W (2014) Kidney protein profiling of Wilms' tumor patients by analysis of formalin-fixed paraffin-embedded tissue samples. Clin Chim Acta. 433:235-41. ArtikelPubmedRelated |
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Iuga C, Seicean A, Iancu C, Buiga R, Sappa PK, Völker U, Hammer E (2014) Proteomic identification of potential prognostic biomarkers in resectable pancreatic ductal adenocarcinoma. Proteomics. 14:945-55. ArtikelPubmedRelated |
| Jehmlich N, Golatowski C, Murr A, Salazar G, Dhople VM, Hammer E, Völker U (2014) Comparative evaluation of peptide desalting methods for salivary proteome analysis. Clin Chim Acta. 434:16-20. ArtikelPubmedRelated |
| Surmann K, Laermann V, Zimmann P, Altendorf K, Hammer E (2014) Absolute quantification of the Kdp subunits of by multiple reaction monitoring. Proteomics. 14:1630-8. ArtikelPubmedRelated |
2013
| Ameling S, Herda LR, Hammer E, Steil L, Teumer A, Trimpert C, Dörr M, Kroemer HK, Klingel K, Kandolf R, Völker U, Felix SB (2013) Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy. Eur Heart J. 34:666-75. ArtikelPubmedRelated |
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Feig MA, Hammer E, Völker U, Jehmlich N (2013) In-depth proteomic analysis of the human cerumen-a potential novel diagnostically relevant biofluid. J Proteomics. 83:119-29. ArtikelPubmedRelated |
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Foerster S, Kacprowski T, Dhople VM, Hammer E, Herzog S, Saafan H, Bien-Möller S, Albrecht M, Völker U, Ritter CA (2013) Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. Proteomics. 13:3131-44. ArtikelPubmedRelated |
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Golatowski C, Salazar MG, Dhople VM, Hammer E, Kocher T, Jehmlich N, Völker U (2013) Comparative evaluation of saliva collection methods for proteome analysis. Clin Chim Acta. 419:42-6. ArtikelPubmedRelated |
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Goyal P, Pandey D, Brünnert D, Hammer E, Zygmunt M, Siess W (2013) Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylation. PLoS One. 8:e71769. ArtikelPubmedRelated |
| Hammer E, Darm K, Völker U (2013) Characterization of the human myocardial proteome in dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies. Methods Mol Biol. 1005:67-76. ArtikelPubmedRelated |
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Jehmlich N, Dinh KHD, Gesell-Salazar M, Hammer E, Steil L, Dhople VM, Schurmann C, Holtfreter B, Kocher T, Völker U (2013) Quantitative analysis of the intra- and inter-subject variability of the whole salivary proteome. J Periodontal Res. 48:392-403. ArtikelPubmedRelated |
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Nishtala K, Phong TQ, Steil L, Sauter M, Salazar MG, Kandolf R, Felix SB, Völker U, Klingel K, Hammer E (2013) Proteomic analyses of age related changes in A.BY/SnJ mouse hearts. Proteome Sci. 11:29. ArtikelPubmedRelated |
| Pförtner H, Wagner J, Surmann K, Hildebrandt P, Ernst S, Bernhardt J, Schurmann C, Gutjahr M, Depke M, Jehmlich U, Dhople V, Hammer E, Steil L, Völker U, Schmidt F (2013) A proteomics workflow for quantitative and time-resolved analysis of adaptation reactions of internalized bacteria. Methods. 61:244-50. ArtikelPubmedRelated |
| Salazar MG, Jehmlich N, Murr A, Dhople VM, Holtfreter B, Hammer E, Völker U, Kocher T (2013) Identification of periodontitis associated changes in the proteome of whole human saliva by mass spectrometric analysis. J Clin Periodontol. 40:825-32. ArtikelPubmedRelated |
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Schlüter R, Lippmann R, Hammer E, Gesell Salazar M, Schauer F (2013) Novel insights into the fungal oxidation of monoaromatic and biarylic environmental pollutants by characterization of two new ring cleavage enzymes. Appl Microbiol Biotechnol. 97:5043-53. ArtikelPubmedRelated |
2012
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Bieler S, Hammer E, Gesell-Salazar M, Völker U, Stangl K, Meiners S (2012) Low dose proteasome inhibition affects alternative splicing. J Proteome Res. 11:3947-54. ArtikelPubmedRelated |
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Ebermann L, Wika S, Klumpe I, Hammer E, Klingel K, Lassner D, Völker U, Erben U, Zeichhardt H, Schultheiss H, Dörner A (2012) The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis. Lab Invest. 92:125-34. ArtikelPubmedRelated |
| Hammer E, Phong TQ, Steil L, Gesell Salazar M, Scharf C, Kandolf R, Felix SB, Kroemer HK, Klingel K, Völker U (2012) Comparative immunoproteome analysis of the response of susceptible A.BY/SnJ and resistant C57BL/6 mice to Coxsackievirus B3-infection J Integr OMICS. 2:54-63. ArtikelPubmedRelated |
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Hussner J, Ameling S, Hammer E, Herzog S, Steil L, Schwebe M, Niessen J, Schroeder HWS, Kroemer HK, Ritter CA, Völker U, Bien S (2012) Regulation of interferon-inducible proteins by doxorubicin via interferon $\gamma$-Janus tyrosine kinase-signal transducer and activator of transcription signaling in tumor cells. Mol Pharmacol. 81:679-88. ArtikelPubmedRelated |
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Mikolasch A, Manda K, Schlüter R, Lalk M, Witt S, Seefeldt S, Hammer E, Schauer F, Jülich W, Lindequist U (2012) Comparative analyses of laccase-catalyzed amination reactions for production of novel $\beta$-lactam antibiotics. Biotechnol Appl Biochem. 59:295-306. ArtikelPubmedRelated |
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Reimer J, Bien S, Ameling S, Hammer E, Völker U, Hempel G, Boos J, Kroemer HK, Ritter CA (2012) Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis. Eur J Clin Microbiol Infect Dis. 68:923-35. ArtikelPubmedRelated |
| Samal R, Ameling S, Wenzel K, Dhople V, Völker U, Felix SB, Könemann S, Hammer E (2012) OMICS-based exploration of the molecular phenotype of resident cardiac progenitor cells from adult murine heart. J Proteomics. 75:5304-15. ArtikelPubmedRelated |
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Visa M, Hammer E, Völker U, Koliwer-Brandl H, Kelm S, Nadimpalli SK (2012) Purification and biochemical characterization of a lysosomal $\alpha$-fucosidase from the deuterostomia Asterias rubens. Biochimie. 94:1199-205. ArtikelPubmedRelated |
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Wünsche A, Hammer E, Bartholomae M, Völker U, Burkovski A, Seidel G, Hillen W (2012) CcpA forms complexes with CodY and RpoA in . FEBS J. 279:2201-14. ArtikelPubmedRelated |
2011
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Gebhard S, Steil L, Peters B, Gesell-Salazar M, Hammer E, Kuttler B, Clemetson KJ, Scharf C, Peters J, Völker U, Rettig R, Greinacher A (2011) Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. J Hypertens. 29:2126-37. ArtikelPubmedRelated |
| Hammer E, Goritzka M, Ameling S, Darm K, Steil L, Klingel K, Trimpert C, Herda LR, Dörr M, Kroemer HK, Kandolf R, Staudt A, Felix SB, Völker U (2011) Characterization of the human myocardial proteome in inflammatory dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies. J Proteome Res. 10:2161-71. ArtikelPubmedRelated |
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Meyer FM, Gerwig J, Hammer E, Herzberg C, Commichau FM, Völker U, Stülke J (2011) Physical interactions between tricarboxylic acid cycle enzymes in : evidence for a metabolon. Metab Eng. 13:18-27. ArtikelPubmedRelated |
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Nishtala K, Phong TQ, Steil L, Sauter M, Salazar MG, Kandolf R, Kroemer HK, Felix SB, Völker U, Klingel K, Hammer E (2011) Virus-induced dilated cardiomyopathy is characterized by increased levels of fibrotic extracellular matrix proteins and reduced amounts of energy-producing enzymes. Proteomics. 11:4310-20. ArtikelPubmedRelated |
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Westermann D, Savvatis K, Lindner D, Zietsch C, Becher PM, Hammer E, Heimesaat MM, Bereswill S, Völker U, Escher F, Riad A, Plendl J, Klingel K, Poller W, Schultheiss H, Tschöpe C (2011) Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Circulation. 124:2082-93. ArtikelPubmedRelated |
2010
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Greinacher A, Wesche J, Hammer E, Fürll B, Völker U, Reil A, Bux J (2010) Characterization of the human neutrophil alloantigen-3a. Nat Med. 16:45-8. ArtikelPubmedRelated |
| Hammer E, Bien S, Salazar MG, Steil L, Scharf C, Hildebrandt P, Schroeder HWS, Kroemer HK, Völker U, Ritter CA (2010) Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches. Proteomics. 10:99-114. ArtikelPubmedRelated |
| Hammer E, Phong TQ, Steil L, Klingel K, Salazar MG, Bernhardt J, Kandolf R, Kroemer HK, Felix SB, Völker U (2010) Viral myocarditis induced by Coxsackievirus B3 in A.BY/SnJ mice: analysis of changes in the myocardial proteome. Proteomics. 10:1802-18. ArtikelPubmedRelated |
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Karanam NK, Grabarczyk P, Hammer E, Scharf C, Venz S, Gesell-Salazar M, Barthlen W, Przybylski GK, Schmidt CA, Völker U (2010) Proteome analysis reveals new mechanisms of Bcl11b-loss driven apoptosis. J Proteome Res. 9:3799-811. ArtikelPubmedRelated |
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Köck K, Koenen A, Giese B, Fraunholz M, May K, Siegmund W, Hammer E, Völker U, Jedlitschky G, Kroemer HK, Grube M (2010) Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization. J Biol Chem. 285:11336-47. ArtikelPubmedRelated |
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Mikolasch A, Hahn V, Manda K, Pump J, Illas N, Gördes D, Lalk M, Gesell Salazar M, Hammer E, Jülich W, Rawer S, Thurow K, Lindequist U, Schauer F (2010) Laccase-catalyzed cross-linking of amino acids and peptides with dihydroxylated aromatic compounds. Amino Acids. 39:671-83. ArtikelPubmedRelated |
| Schmidt F, Scharf SS, Hildebrandt P, Burian M, Bernhardt J, Dhople V, Kalinka J, Gutjahr M, Hammer E, Völker U (2010) Time-resolved quantitative proteome profiling of host-pathogen interactions: the response of Staphylococcus aureus RN1HG to internalisation by human airway epithelial cells. Proteomics. 10:2801-11. ArtikelPubmedRelated |